Genetic implication of a novel thiamine transporter in human hypertension

OBJECTIVES: We coupled two strategies – trait extremes and genome-wide pooling – to discover a novel BP locus that encodes a previously uncharacterized thiamine transporter. BACKGROUND: Hypertension is a heritable trait that remains the most potent and widespread cardiovascular risk factor, though d...

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Detalhes bibliográficos
Main Authors: Zhang, Kuixing, Huentelman, Matthew J., Rao, Fangwen, Sun, Eric I., Corneveaux, Jason J., Schork, Andrew J., Wei, Zhiyun, Waalen, Jill, Miramontes-Gonzalez, Jose Pablo, Hightower, C. Makena, Maihofer, Adam X., Mahata, Manjula, Pastinen, Tomi, Ehret, Georg B., Schork, Nicholas J., Eskin, Eleazar, Nievergelt, Caroline M., Saier, Milton H., O'Connor, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992204/
https://ncbi.nlm.nih.gov/pubmed/24509276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.01.007
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