Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3′-Untranslated Region Polymorphism C+87T by MicroRNA-107

Chromogranin A (CHGA) is coreleased with catecholamines from secretory vesicles in adrenal medulla and sympathetic axons. Genetic variation in the CHGA 3′-region has been associated with autonomic control of circulation, hypertension, and hypertensive nephropathy, and the CHGA 3′-untranslated region...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Zhang, Kuixing, Mir, Saiful A., Hightower, C. Makena, Miramontes-Gonzalez, Jose Pablo, Maihofer, Adam X., Chen, Yuqing, Mahata, Sushil K., Nievergelt, Caroline M., Schork, Nicholas J., Freedman, Barry I., Vaingankar, Sucheta M., O'Connor, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520173/
https://ncbi.nlm.nih.gov/pubmed/25392232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014060537
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