Naturally occurring human genetic variation in the 3’-untranslated region of the secretory protein chromogranin A (CHGA) is associated with autonomic blood pressure regulation and hypertension in sex-dependent fashion

OBJECTIVE: Determination whether common variation at the CHGA locus increases susceptibility to hypertension. BACKGROUND: Chromogranin A (CHGA) regulates catecholamine storage and release. Previously we systematically identified genetic variants across CHGA. METHODS: Dense genotyping across the CHGA...

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Bibliografiset tiedot
Päätekijät: Chen, Yuqing, Rao, Fangwen, Rodriguez-Flores, Juan L., Mahata, Manjula, Fung, Maple M., Stridsberg, Mats, Vaingankar, Sucheta M., Wen, Gen, Salem, Rany M., Das, Madhusudan, Cockburn, Myles G., Schork, Nicholas J., Ziegler, Michael G., Hamilton, Bruce A., Mahata, Sushil K., Taupenot, Laurent, O’Connor, Daniel T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659417/
https://ncbi.nlm.nih.gov/pubmed/19017515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2008.07.047
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