Naturally occurring human genetic variation in the 3’-untranslated region of the secretory protein chromogranin A (CHGA) is associated with autonomic blood pressure regulation and hypertension in sex-dependent fashion

OBJECTIVE: Determination whether common variation at the CHGA locus increases susceptibility to hypertension. BACKGROUND: Chromogranin A (CHGA) regulates catecholamine storage and release. Previously we systematically identified genetic variants across CHGA. METHODS: Dense genotyping across the CHGA...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Yuqing, Rao, Fangwen, Rodriguez-Flores, Juan L., Mahata, Manjula, Fung, Maple M., Stridsberg, Mats, Vaingankar, Sucheta M., Wen, Gen, Salem, Rany M., Das, Madhusudan, Cockburn, Myles G., Schork, Nicholas J., Ziegler, Michael G., Hamilton, Bruce A., Mahata, Sushil K., Taupenot, Laurent, O’Connor, Daniel T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659417/
https://ncbi.nlm.nih.gov/pubmed/19017515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2008.07.047
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