Chromogranin A Regulates Renal Function by Triggering Weibel–Palade Body Exocytosis

Chromogranin A (CHGA), a protein released from secretory granules of chromaffin cells and sympathetic nerves, triggers endothelin-1 release from endothelial cells. CHGA polymorphisms associate with an increased risk for ESRD, but whether altered CHGA–endothelium interactions may explain this associa...

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Autores principales: Chen, Yuqing, Mahata, Manjula, Rao, Fangwen, Khandrika, Srikrishna, Courel, Maite, Fung, Maple M., Zhang, Kuixing, Stridsberg, Mats, Ziegler, Michael G., Hamilton, Bruce A., Lipkowitz, Michael S., Taupenot, Laurent, Nievergelt, Caroline, Mahata, Sushil K., O'Connor, Daniel T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2009
Materias:
Clinical Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709688/
https://ncbi.nlm.nih.gov/pubmed/19520754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008111148
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