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Sphingosine 1-phosphate activates Weibel-Palade body exocytosis

Sphingosine 1-phosphate (S1P) not only regulates angiogenesis, vascular permeability and vascular tone, but it also promotes vascular inflammation. However, the molecular basis for the proinflammatory effects of S1P is not understood. We now show that S1P activates endothelial cell exocytosis of Wei...

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Détails bibliographiques
Auteurs principaux: Matsushita, Kenji, Morrell, Craig N., Lowenstein, Charles J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC509226/
https://ncbi.nlm.nih.gov/pubmed/15273282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400185101
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