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Sphingosine 1-phosphate activates Weibel-Palade body exocytosis

Sphingosine 1-phosphate (S1P) not only regulates angiogenesis, vascular permeability and vascular tone, but it also promotes vascular inflammation. However, the molecular basis for the proinflammatory effects of S1P is not understood. We now show that S1P activates endothelial cell exocytosis of Wei...

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Autores principales: Matsushita, Kenji, Morrell, Craig N., Lowenstein, Charles J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC509226/
https://ncbi.nlm.nih.gov/pubmed/15273282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400185101
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