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Functional consequences of inhibiting exocytosis of Weibel-Palade bodies in acute renal ischemia

Exocytosis of Weibel-Palade bodies (WPB) represents a distinct response of endothelial cells to stressors, and local release of WPB contents leads to systemic escalation of this response. We synthesized a glycine-(Nα-Et)lysine-proline-arginine (ITF 1697) peptide that has a potential to inhibit exocy...

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Detalhes bibliográficos
Main Authors: Yasuda, Kaoru, Vasko, Radovan, Hayek, Peter, Ratliff, Brian, Bicer, Hasan, Mares, Jonathan, Maruyama, Shoichi, Bertuglia, Silvia, Mascagni, Paolo, Goligorsky, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311315/
https://ncbi.nlm.nih.gov/pubmed/22160777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00541.2011
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