Chromogranin B (CHGB): Intra- and extra-cellular mechanisms to regulate catecholamine storage and release, in catecholaminergic cells and organisms

CHGB is the major matrix protein in human catecholamine storage vesicles. CHGB genetic variation alters catecholamine secretion and blood pressure. Here effective Chgb protein under-expression was achieved by siRNA in PC12 cells, resulting in ~48% fewer secretory granules on EM, diminished capacity...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Kuixing, Biswas, Nilima, Gayen, Jiaur R., Miramontes-Gonzalez, Jose Pablo, Hightower, C. Makena, Mustapic, Maja, Mahata, Manjula, Huang, Chun-Teng, Hook, Vivian Y., Mahata, Sushil K., Vaingankar, Sucheta, O'Connor, Daniel T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992281/
https://ncbi.nlm.nih.gov/pubmed/24266713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12527
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