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Effects of chromogranin A Deficiency and Excess in vivo: Biphasic Blood Pressure and Catecholamine Responses

OBJECTIVE: The phenotype of the Chromogranin A(Chga) null (knockout) mouse is hypertensive. However, hypertensive humans and spontaneously hypertensive rats display elevated CHGA expression. This study addresses the paradox that both ablation and elevation of CHGA result in hypertension. METHODS: Mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Vaingankar, Sucheta M., Li, Ying, Biswas, Nilima, Gayen, Jiaur, Choksi, Sonia, Rao, Fangwen, Ziegler, Michael G., Mahata, Sushil K., O'Connor, Daniel T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947860/
https://ncbi.nlm.nih.gov/pubmed/20139771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e328336ed3e
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