Effects of chromogranin A Deficiency and Excess in vivo: Biphasic Blood Pressure and Catecholamine Responses

OBJECTIVE: The phenotype of the Chromogranin A(Chga) null (knockout) mouse is hypertensive. However, hypertensive humans and spontaneously hypertensive rats display elevated CHGA expression. This study addresses the paradox that both ablation and elevation of CHGA result in hypertension. METHODS: Mi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Vaingankar, Sucheta M., Li, Ying, Biswas, Nilima, Gayen, Jiaur, Choksi, Sonia, Rao, Fangwen, Ziegler, Michael G., Mahata, Sushil K., O'Connor, Daniel T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947860/
https://ncbi.nlm.nih.gov/pubmed/20139771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e328336ed3e
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge