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Cathepsin L Colocalizes with Chromogranin A in Chromaffin Vesicles to Generate Active Peptides

Chromogranin A (CgA), the major soluble protein in chromaffin granules, is proteolytically processed to generate biologically active peptides including the catecholamine release inhibitory peptide catestatin. Here we sought to determine whether cysteine protease cathepsin L (CTSL), a novel enzyme fo...

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Bibliographic Details
Main Authors: Biswas, Nilima, Rodriguez-Flores, Juan L., Courel, Maite, Gayen, Jiaur R., Vaingankar, Sucheta M., Mahata, Manjula, Torpey, Justin W., Taupenot, Laurent, O'Connor, Daniel T., Mahata, Sushil K.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717865/
https://ncbi.nlm.nih.gov/pubmed/19372204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1613
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