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Cathepsin L Colocalizes with Chromogranin A in Chromaffin Vesicles to Generate Active Peptides

Chromogranin A (CgA), the major soluble protein in chromaffin granules, is proteolytically processed to generate biologically active peptides including the catecholamine release inhibitory peptide catestatin. Here we sought to determine whether cysteine protease cathepsin L (CTSL), a novel enzyme fo...

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Autors principals: Biswas, Nilima, Rodriguez-Flores, Juan L., Courel, Maite, Gayen, Jiaur R., Vaingankar, Sucheta M., Mahata, Manjula, Torpey, Justin W., Taupenot, Laurent, O'Connor, Daniel T., Mahata, Sushil K.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717865/
https://ncbi.nlm.nih.gov/pubmed/19372204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1613
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