Discovery of a Novel Target for the Dysglycemic Chromogranin A Fragment Pancreastatin: Interaction with the Chaperone GRP78 to Influence Metabolism

RATIONALE: The chromogranin A-derived peptide pancreastatin (PST) is a dysglycemic, counter-regulatory peptide for insulin action, especially in liver. Although previous evidence for a PST binding protein has been reported, such a receptor has not been identified or sequenced. METHODS AND RESULTS: W...

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Bibliographic Details
Main Authors: Biswas, Nilima, Friese, Ryan S., Gayen, Jiaur R., Bandyopadhyay, Gautam, Mahata, Sushil K., O'Connor, Daniel T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896336/
https://ncbi.nlm.nih.gov/pubmed/24465394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084132
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