Neural tube defects and abnormal brain development in F52-deficient mice.
F52 is a myristoylated, alanine-rich substrate for protein kinase C. We have generated F52-deficient mice by the gene targeting technique. These mutant mice manifest severe neural tube defects that are not associated with other complex malformations, a phenotype reminiscent of common human neural tu...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1996
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2110 |
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