Neural tube defects and abnormal brain development in F52-deficient mice.

F52 is a myristoylated, alanine-rich substrate for protein kinase C. We have generated F52-deficient mice by the gene targeting technique. These mutant mice manifest severe neural tube defects that are not associated with other complex malformations, a phenotype reminiscent of common human neural tu...

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I whakaputaina i:	Proc Natl Acad Sci U S A
Ngā kaituhi matua:	Wu, M, Chen, D F, Sasaoka, T, Tonegawa, S
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	National Academy of Sciences 1996
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2110
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