Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

Although cyclin-dependent kinase 5 (Cdk5) is closely related to other cyclin-dependent kinases, its kinase activity is detected only in the postmitotic neurons. Cdk5 expression and kinase activity are correlated with the extent of differentiation of neuronal cells in developing brain. Cdk5 purified...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ohshima, T, Ward, J M, Huh, C G, Longenecker, G, Veeranna, Pant, H C, Brady, R O, Martin, L J, Kulkarni, A B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.11173
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!