Stable overexpression of miR-17 enhances recombinant protein production of CHO cells()

miRNAs negatively regulate gene expression at post-transcriptional level, and consequently play an important role in the control of many cellular pathways. The use of miRNAs to engineer Chinese hamster ovary (CHO) cells is an emerging strategy to improve recombinant protein production. Here, we desc...

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Hlavní autoři: Jadhav, Vaibhav, Hackl, Matthias, Klanert, Gerald, Hernandez Bort, Juan A., Kunert, Renate, Grillari, Johannes, Borth, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science Publishers 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991393/
https://ncbi.nlm.nih.gov/pubmed/24518263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.01.032
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