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Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation
CHO cells are the mammalian cell line of choice for recombinant production of therapeutic proteins. However, their low rate of proliferation limits obtainable space-time yields due to inefficient biomass accumulation. We set out to correlate microRNA transcription to cell-specific growth-rate by mic...
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| Gepubliceerd in: | J Biotechnol |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Elsevier Science Publishers
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247382/ https://ncbi.nlm.nih.gov/pubmed/24486028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2013.12.018 |
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