Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

CHO cells are the mammalian cell line of choice for recombinant production of therapeutic proteins. However, their low rate of proliferation limits obtainable space-time yields due to inefficient biomass accumulation. We set out to correlate microRNA transcription to cell-specific growth-rate by mic...

Full description

Saved in:
Bibliographic Details
Published in:J Biotechnol
Main Authors: Hackl, Matthias, Jadhav, Vaibhav, Klanert, Gerald, Karbiener, Michael, Scheideler, Marcel, Grillari, Johannes, Borth, Nicole
Format: Artigo
Language:Inglês
Published: Elsevier Science Publishers 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247382/
https://ncbi.nlm.nih.gov/pubmed/24486028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2013.12.018
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items