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Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

CHO cells are the mammalian cell line of choice for recombinant production of therapeutic proteins. However, their low rate of proliferation limits obtainable space-time yields due to inefficient biomass accumulation. We set out to correlate microRNA transcription to cell-specific growth-rate by mic...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Biotechnol
Asıl Yazarlar: Hackl, Matthias, Jadhav, Vaibhav, Klanert, Gerald, Karbiener, Michael, Scheideler, Marcel, Grillari, Johannes, Borth, Nicole
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Science Publishers 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247382/
https://ncbi.nlm.nih.gov/pubmed/24486028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2013.12.018
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