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Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells
MicroRNAs (miRNAs) are small non-coding RNAs (∼22 nucleotides) which regulate gene expression by silencing mRNA translation. MiRNAs are transcribed as long primary transcripts, which are enzymatically processed by Drosha/Dgcr8, in the nucleus, and by Dicer in the cytoplasm, into mature miRNAs. The i...
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| Publié dans: | Biotechnol J |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY-VCH Verlag
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282078/ https://ncbi.nlm.nih.gov/pubmed/24323929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201300216 |
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