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Stable overexpression of miR-17 enhances recombinant protein production of CHO cells()

miRNAs negatively regulate gene expression at post-transcriptional level, and consequently play an important role in the control of many cellular pathways. The use of miRNAs to engineer Chinese hamster ovary (CHO) cells is an emerging strategy to improve recombinant protein production. Here, we desc...

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Detalhes bibliográficos
Main Authors: Jadhav, Vaibhav, Hackl, Matthias, Klanert, Gerald, Hernandez Bort, Juan A., Kunert, Renate, Grillari, Johannes, Borth, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991393/
https://ncbi.nlm.nih.gov/pubmed/24518263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.01.032
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