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miR-17–92 cluster: ups and downs in cancer and aging
The miR-17–92 cluster encoding 6 single mature miRNAs was identified a couple of years ago to contain the first oncogenic miRNAs. Now, one of these 6 miRNAs, miR-19 has been identified as the key responsible for this oncogenic activity. This in turn reduces PTEN levels and in consequence activates t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Netherlands
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2899009/ https://ncbi.nlm.nih.gov/pubmed/20437201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-010-9272-9 |
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