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PIAS1 SUMO ligase regulates the self-renewal and differentiation of hematopoietic stem cells
The selective and temporal DNA methylation plays an important role in the self-renewal and differentiation of hematopoietic stem cells (HSCs), but the molecular mechanism that controls the dynamics of DNA methylation is not understood. Here, we report that the PIAS1 epigenetic pathway plays an impor...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989605/ https://ncbi.nlm.nih.gov/pubmed/24357619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201283326 |
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