A Transcriptional Repressor ZBTB1 Promotes Chromatin Remodeling and Translesion DNA Synthesis

Timely DNA replication across damaged DNA is critical for maintaining genomic integrity. Translesion DNA synthesis (TLS) allows bypass of DNA lesions using error-prone TLS polymerases. The E3 ligase RAD18 is necessary for PCNA monoubiquitination and TLS polymerase recruitment; however, the regulator...

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Autores principales: Kim, Hyungjin, Dejsuphong, Donniphat, Adelmant, Guillaume, Ceccaldi, Raphael, Yang, Kailin, Marto, Jarrod A., D’Andrea, Alan D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989074/
https://ncbi.nlm.nih.gov/pubmed/24657165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.017
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