A Transcriptional Repressor ZBTB1 Promotes Chromatin Remodeling and Translesion DNA Synthesis

Timely DNA replication across damaged DNA is critical for maintaining genomic integrity. Translesion DNA synthesis (TLS) allows bypass of DNA lesions using error-prone TLS polymerases. The E3 ligase RAD18 is necessary for PCNA monoubiquitination and TLS polymerase recruitment; however, the regulator...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Hyungjin, Dejsuphong, Donniphat, Adelmant, Guillaume, Ceccaldi, Raphael, Yang, Kailin, Marto, Jarrod A., D’Andrea, Alan D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989074/
https://ncbi.nlm.nih.gov/pubmed/24657165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.017
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