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The Chromatin Remodeling Factor CHD5 Is a Transcriptional Repressor of WEE1

Loss of the chromatin remodeling ATPase CHD5 has been linked to the progression of neuroblastoma tumors, yet the underlying mechanisms behind the tumor suppressor role of CHD5 are unknown. In this study, we purified the human CHD5 complex and found that CHD5 is a component of the full NuRD transcrip...

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Autori principali: Quan, Jinhua, Adelmant, Guillaume, Marto, Jarrod A., Look, A. Thomas, Yusufzai, Timur
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172601/
https://ncbi.nlm.nih.gov/pubmed/25247294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108066
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