A Transcriptional Repressor ZBTB1 Promotes Chromatin Remodeling and Translesion DNA Synthesis

Timely DNA replication across damaged DNA is critical for maintaining genomic integrity. Translesion DNA synthesis (TLS) allows bypass of DNA lesions using error-prone TLS polymerases. The E3 ligase RAD18 is necessary for PCNA monoubiquitination and TLS polymerase recruitment; however, the regulator...

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Main Authors: Kim, Hyungjin, Dejsuphong, Donniphat, Adelmant, Guillaume, Ceccaldi, Raphael, Yang, Kailin, Marto, Jarrod A., D’Andrea, Alan D.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989074/
https://ncbi.nlm.nih.gov/pubmed/24657165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.017
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