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BRG1 Chromatin Remodeling Activity is Required for Efficient Chromatin Binding by the Transcriptional Repressor Rest and Facilitates Rest-Mediated Repression

Chromatin remodeling enzymes, such as SWI/SNF, use the hydrolysis of ATP to power the movement of nucleosomes with respect to DNA. BRG1, one of the ATPases of the SWI/SNF complex can be recruited by both activators and repressors, though the precise role of BRG1 in mechanisms of repression has thus...

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Bibliographische Detailangaben
Hauptverfasser: Ooi, Lezanne, Belyaev, Nikolai D., Miyake, Katsuhide, Wood, Ian C., Buckley, Noel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820614/
https://ncbi.nlm.nih.gov/pubmed/17023429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605370200
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