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Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism

Previous studies have shown that whole body deletion of the glucagon receptor suppresses the ability of starvation to increase hepatic fibroblast growth factor 21 (FGF21) expression and plasma FGF21 concentration. Here, we investigate the mechanism by which glucagon receptor activation increases hep...

詳細記述

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書誌詳細
主要な著者: Cyphert, Holly A., Alonge, Kimberly M., Ippagunta, Siri M., Hillgartner, F. Bradley
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986400/
https://ncbi.nlm.nih.gov/pubmed/24733293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094996
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