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Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism

Previous studies have shown that whole body deletion of the glucagon receptor suppresses the ability of starvation to increase hepatic fibroblast growth factor 21 (FGF21) expression and plasma FGF21 concentration. Here, we investigate the mechanism by which glucagon receptor activation increases hep...

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Detaylı Bibliyografya
Asıl Yazarlar: Cyphert, Holly A., Alonge, Kimberly M., Ippagunta, Siri M., Hillgartner, F. Bradley
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986400/
https://ncbi.nlm.nih.gov/pubmed/24733293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094996
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