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Individual I(Ks) channels at the surface of mammalian cells contain two KCNE1 accessory subunits
KCNE1 (E1) β-subunits assemble with KCNQ1 (Q1) voltage-gated K(+) channel α-subunits to form I(Kslow) (I(Ks)) channels in the heart and ear. The number of E1 subunits in I(Ks) channels has been an issue of ongoing debate. Here, we use single-molecule spectroscopy to demonstrate that surface I(Ks) ch...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986162/ https://ncbi.nlm.nih.gov/pubmed/24591645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323548111 |
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