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Sumoylation Silences Heterodimeric TASK Potassium Channels Containing K2P1 Subunits in Cerebellar Granule Neurons
The standing outward K(+) current (IKso) governs the response of cerebellar granule neurons to natural and medicinal stimuli including volatile anesthetics. In this study, we showed that sumoylation silenced half of IKso at the surface of cerebellar granule neurons because the underlying channels we...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876883/ https://ncbi.nlm.nih.gov/pubmed/23169818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003431 |
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