A carregar...
SUMOylation of Na(V)1.2 channels mediates the early response to acute hypoxia in central neurons
The mechanism for the earliest response of central neurons to hypoxia—an increase in voltage-gated sodium current (I(Na))—has been unknown. Here, we show that hypoxia activates the Small Ubiquitin-like Modifier (SUMO) pathway in rat cerebellar granule neurons (CGN) and that SUMOylation of Na(V)1.2 c...
Na minha lista:
| Publicado no: | eLife |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283832/ https://ncbi.nlm.nih.gov/pubmed/28029095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20054 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|