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Impact of Bilayer Lipid Composition on the Structure and Topology of the Transmembrane Amyloid Precursor C99 Protein

[Image: see text] C99 (also known as β-CTF) is the 99 residue transmembrane C-terminal domain (residues 672–770) of the amyloid precursor protein and is the immediate precursor of the amyloid-β (Aβ) polypeptides. To test the dependence of the C99 structure on the composition of the host model membra...

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Detalhes bibliográficos
Main Authors: Song, Yuanli, Mittendorf, Kathleen F., Lu, Zhenwei, Sanders, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985881/
https://ncbi.nlm.nih.gov/pubmed/24564538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4114374
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