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Notch Transmembrane Domain: Secondary Structure and Topology
[Image: see text] The Notch signaling pathway is critical in development, neuronal maintenance, and hematopoiesis. An obligate step in the activation of this pathway is cleavage of its transmembrane (TM) domain by γ-secretase. While the soluble domains have been extensively studied, little has been...
Gardado en:
| Publicado en: | Biochemistry |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American
Chemical Society
2015
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472088/ https://ncbi.nlm.nih.gov/pubmed/26023825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00456 |
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