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Concise Enantiospecific Total Synthesis of Tubingensin A
[Image: see text] We report the enantiospecific total synthesis of (+)-tubingensin A. Our synthesis features an aryne cyclization to efficiently introduce the vicinal quaternary stereocenters of the natural product and proceeds in only nine steps (longest linear sequence) from known compounds.
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2014
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985696/ https://ncbi.nlm.nih.gov/pubmed/24524351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501142e |
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