Llwytho...

Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase using microinjection into live cells

Oncogenic mutations in PIK3CA lead to an increase in intrinsic phosphoinositide kinase activity, but it is thought that increased access of PI3Kα (phosphoinositide 3-kinase α) to its PM (plasma membrane) localized substrate is also required for increased levels of downstream PIP(3)/Akt [phosphoinosi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Layton, Meredith J., Rynkiewicz, Natalie K., Ivetac, Ivan, Horan, Kristy A., Mitchell, Christina A., Phillips, Wayne A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985441/
https://ncbi.nlm.nih.gov/pubmed/27919038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130133
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