Synthesis of a 2-Aryl-3-Aroyl-Indole Salt (OXi8007) Resembling Combretastatin A-4 with Application as a Vascular Disrupting Agent

The natural products colchicine and combretastatin A-4 (CA4) are potent inhibitors of tubulin assembly, and they have inspired the design and synthesis of a large number of small-molecule, potential anticancer agents. The indole-based molecular scaffold is prominent among these SAR modifications, le...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Hadimani, Mallinath B., MacDonough, Matthew T., Ghatak, Anjan, Strecker, Tracy E., Lopez, Ramona, Sriram, Madhavi, Nguyen, Benson L., Hall, John J., Kessler, Raymond J., Shirali, Anupama R., Liu, Li, Garner, Charles M., Pettit, George R., Hamel, Ernest, Chaplin, David J., Mason, Ralph P., Trawick, Mary Lynn, Pinney, Kevin G.
格式: Artigo
語言:Inglês
出版: 2013
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985392/
https://ncbi.nlm.nih.gov/pubmed/24016002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400374w
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍