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Genetic Assessment of the Role of AcrB β-Hairpins in the Assembly of the TolC-AcrAB Multidrug Efflux Pump of Escherichia coli

The tripartite AcrAB-TolC multidrug efflux-pump of Escherichia coli is the central conduit for cell-toxic compounds and contributes to antibiotic resistance. While high-resolution structures of all three proteins have been solved, much remains to be learned as to how the individual components come t...

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Autores principales: Weeks, Jon W., Bavro, Vassiliy N., Misra, Rajeev
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984920/
https://ncbi.nlm.nih.gov/pubmed/24386963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12508
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