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Mutations in the TolC Periplasmic Domain Affect Substrate Specificity of the AcrAB-TolC Pump
TolC and the other members of the outer membrane factor (OMF) family are outer membrane proteins forming trimeric channels that serve as a conduit for most actively effluxed substrates in Gram-negative bacteria by providing a key component in a multitude of tripartite efflux-pumps. Current models of...
Enregistré dans:
| Publié dans: | Front Mol Biosci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7396618/ https://ncbi.nlm.nih.gov/pubmed/32850959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00166 |
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