Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells

During prion diseases, a normally benign, host protein, denoted PrP(C), undergoes alternative folding into the aberrant isoform, PrP(Sc). We used ELISA assays to identify and confirm hits in order to develop leads that reduce PrP(Sc) in prion-infected dividing and stationary-phase mouse neuroblastom...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Silber, B. Michael, Gever, Joel R., Li, Zhe, Gallardo-Godoy, Alejandra, Renslo, Adam R., Widjaja, Kartika, Irwin, John J., Rao, Satish, Jacobson, Matthew P., Ghaemmaghami, Sina, Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984054/
https://ncbi.nlm.nih.gov/pubmed/24183589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.09.022
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker