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Discovery of 2-Aminothiazoles as Potent Antiprion Compounds
Prion diseases are fatal, untreatable neurodegenerative diseases caused by the accumulation of the misfolded, infectious isoform of the prion protein (PrP), termed PrP(Sc). In an effort to identify novel inhibitors of prion formation, we utilized a high-throughput enzyme-linked immunosorbent assay (...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838138/ https://ncbi.nlm.nih.gov/pubmed/20032192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02145-09 |
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