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Is Alzheimer’s disease amyloidosis the result of a repair mechanism gone astray?

We synthesize several lines of evidence supporting the hypothesis that at least one function of Aβ is to serve as a part of the acute response to brain hemodynamic disturbances intended to seal vascular leakage. Given the resilient and adhesive physicochemical properties of amyloid, an abluminal hem...

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Main Authors: Kokjohn, Tyler A., Maarouf, Chera L., Roher, Alex E.
格式: Artigo
語言:Inglês
出版: 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984046/
https://ncbi.nlm.nih.gov/pubmed/22047632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2011.05.2429
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