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Is Alzheimer’s disease amyloidosis the result of a repair mechanism gone astray?

We synthesize several lines of evidence supporting the hypothesis that at least one function of Aβ is to serve as a part of the acute response to brain hemodynamic disturbances intended to seal vascular leakage. Given the resilient and adhesive physicochemical properties of amyloid, an abluminal hem...

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Autors principals: Kokjohn, Tyler A., Maarouf, Chera L., Roher, Alex E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984046/
https://ncbi.nlm.nih.gov/pubmed/22047632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2011.05.2429
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