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Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery
Designer nucleases, like zinc-finger nucleases (ZFNs), represent valuable tools for targeted genome editing. Here, we took advantage of the gamma-retroviral life cycle and produced vectors to transfer ZFNs in the form of protein, mRNA and episomal DNA. Transfer efficacy and ZFN activity were assesse...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983605/ https://ncbi.nlm.nih.gov/pubmed/24722320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04656 |
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