Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway

Forkhead box O (FoxO) transcription factors play an important role as tumor suppressor in several human malignancies. Disruption of FoxO activity due to loss of phosphatase and tensin homolog and activation of phosphatidylinositol-3 kinase (PI3K)/Akt are frequently observed in prostate cancer. Apige...

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Bibliographische Detailangaben
Hauptverfasser: Shukla, Sanjeev, Bhaskaran, Natarajan, Babcook, Melissa A., Fu, Pingfu, MacLennan, Gregory T., Gupta, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Original Manuscript
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983429/
https://ncbi.nlm.nih.gov/pubmed/24067903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt316
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