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Apigenin attenuates insulin-like growth factor-I signaling in an autochthonous mouse prostate cancer model
PURPOSE: Deregulation of IGF signaling plays an important role in prostate cancer and contributes to invasion and metastasis. We determined the effect of apigenin, a plant flavone, on IGF signaling and its downstream targets in TRAMP mice. METHODS: Mice received p.o. apigenin at 20 and 50µg/day dose...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017263/ https://ncbi.nlm.nih.gov/pubmed/22139534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0625-0 |
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