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Apigenin attenuates insulin-like growth factor-I signaling in an autochthonous mouse prostate cancer model

PURPOSE: Deregulation of IGF signaling plays an important role in prostate cancer and contributes to invasion and metastasis. We determined the effect of apigenin, a plant flavone, on IGF signaling and its downstream targets in TRAMP mice. METHODS: Mice received p.o. apigenin at 20 and 50µg/day dose...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shukla, Sanjeev, MacLennan, Gregory T, Fu, Pingfu, Gupta, Sanjay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017263/
https://ncbi.nlm.nih.gov/pubmed/22139534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0625-0
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