Deregulation of FOXO3A During Prostate Cancer Progression

Forkhead box transcription factor FOXO3A is an important regulator of cellular function, is thought to act as a tumor suppressor. We studied whether alterations in FOXO3A activity occur in prostate tumorigenesis. Our studies demonstrate that FOXO3A activity is negatively regulated by Akt/PKB through...

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Hlavní autoři: Shukla, Sanjeev, Shukla, Meenakshi, MacLennan, Gregory T, Fu, Pingfu, Gupta, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683383/
https://ncbi.nlm.nih.gov/pubmed/19424579
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