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Deregulation of FoxO3a Accelerates Prostate Cancer Progression in TRAMP Mice
BACKGROUND: Forkhead box, class “O” (FoxO) transcription factors are involved in multiple signaling pathways and possess tumor suppressor functions. Loss of PTEN and activation of PI3K/Akt is frequently observed in prostate cancer, which may potentially inactivate FoxO activity. We therefore investi...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018753/ https://ncbi.nlm.nih.gov/pubmed/23765843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22698 |
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